Lyophilic dryers

ENLARGE :: Lyophilic dryers

Q-TECHNOLOGIES GROUP GMBH offers lyophilic dryers under QUARCO trademark for plasma, tissues, proteins, microbial cultures, various medicinal products (antibiotics, anticancer drugs, vitamins, sera, vaccines etc.). Lyophilic dryers are used in laboratories, pharmaceutical, food, veterinary and other facilities.

ENLARGE :: Product vialsENLARGE :: Product vials

Lyophilic dryer principle of action:

Advantages of lyophilic drying:

  • Product is not affected by high temperatures;
  • Produced preparations may be stored for a long time;
  • Preparations preserve structural integrity and biological activity;

Important: Lyophilized tissues and preparations restore their initial properties after wetting.strong>

Lyophilizing principle is based on drying of specimens in frozen state under vacuum so that water is removed from frozen preparations by sublimation – conversion to vapor omitting liquid phase. Water vapor is pumped out of the working camera with vacuum pumps and condenses on low-temperature condenser coils.

Lyophilizing process may be conveniently divided into two phases:

  1. Putting the product in vials (ampoules) or trays on working camera shelves with subsequent deep freezing of product to -40°С – -50°С. First phase of lyophilizing process is critically important as the faster the temperature reaches the set value, the smaller is the volume of produced ice crystals so they faster evaporate at drying step.
  2. Ice evaporation from the frozen solution and its sedimentation in condenser. High vacuum is created in the whole system (working camera and condenser) to provide this process. Vapor is transferred to condenser coil by the difference in partial pressures of water vapor.

Reliable control and process operation system is an important component of QUARCO PHARM & MEDICAL EQUIPMENT lyophilic dryers.

Features of QUARCO PHARM & MEDICAL EQUIPMENT lyophilic dryers:

  1. Well-designed arrangement of all components and units enabling us to make dryers compact and easy to maintain;
  2. Product contacting surfaces are made of stainless steel AISI316L;
  3. Roughness of working camera and condenser inner surfaces is 0.4 μm, smooth polishing;
  4. Roughness of shelves is 0.4 μm, matted polishing;
  5. All welding is made in nitrogen flow with further passivation and thorough polishing of welding joints;
  6. Minimal distance between working camera and condenser in combination with the maximal diameter of the main valve enable altering the path of ice vapor from the product to condenser coil. It shortens ice vapor transfer time from the working camera to condenser coil thus accelerating sublimation and decreasing the drying time;
  7. Effective heat isolation of working camera and condenser enables reduced intensity of compressor work and prevents condensation on the outer surface of equipment;

    ENLARGE :: Camera and condenser heat insulation

  8. Dryer plan can be made to develop the regimen for product drying;
  9. Design of dryer shelves provide even distribution of temperature over the entire shelf surface;
  10. Compressors Bitzer in combination with valves and relays Danfoss result in high robustness of Freon circuits;
УВЕЛИЧИТЬ :: Compressor BitzerENLARGE :: Relay Danfoss
  • Vacuum system may be furnished with vacuum and booster pumps Edwards or Leybold.

    ENLARGE :: Vacuum and booster pumps Edwards

  • Transmitters Thermovac Leybold or APG Edwards enable accurate tracing of all drying steps;

    ENLARGE :: Vacuum probe Pirani Edwards

  • Central operating and control system is made by industrial logical controllers OMRON (optionally, the basic controller may be substituted for PLC Siemens);

    ENLARGE :: Controller OMROM

  • PC-based operator working station with preinstalled Windows operating system (Russian version) provides real-time control and saving of current process parameters: inlet and outlet heat carrier temperature, work shelves’ temperature, temperature of each Freon circuit, pressure in camera and condenser;

    ENLARGE :: Workstation Lenovo

  • All data are registered by paper-free recorder Yokogawa.

    • ENLARGE :: Paperless recorder Yokogawa

    Lyophilic dryer

    Name1234681015203040
    Shelf area, m21,081,972,964,425,537,7510,3314,7620,623042
    Vial load, pcs. Ø16 мм3 8007 50011 00017 000 30 00040 00057 00080 000117 000163 000
    Vial load, pcs. Ø22 мм2 1004 0006 0009 00011 20015 80021 00030 00042 00062 00086 000
    Number of shelves4+14+16+14+15+17+17+110+111+110+114+1
    Shelf size，mm450 х 600610 х 810610 х 810915 x 1210915 x 1210915 x 12101215 x 12151215 x 12151250 x 15001500 x 20001500 x 2000
    Minimal shelf temperature (without product), °С-55
    Condenser performance, kg≥ 20≥ 40≥ 60≥ 80≥ 110≥ 150≥ 200≥ 300≥ 400≥ 600≥ 800
    Minimal condenser temperature (without product), °С-75
    Overall dimensions, mm2600 х 1550 х 24004000 х 1600 х 24004800 x 1600 x 27005300 x 1900 x 25005500 x 1900 x 28006000 x 1900 x 31006500 x 2200 x 31006700 x 2200 x 36007500 x 2300 x 38008000 x 2550 x 36009500 x 2550 x 4500
    Set power, kW1019233338466480111145188
    Weight, kg (without SIP)2 2003 5004 5006 0007 0009 00011 00014 00017 00022 00025 000



    Why is pharmaceutical equipment under QUARCO PHARM & MEDICAL EQUIPMENT trademark chosen?

    Perhaps, this question can be a matter of interest only to potential clients of our company rather than to our loyal clients and partners. The latter are confident in the quality of our production, and for them the choice of pharmaceutical equipment under QUARCO trademark has long been plain as day. So do ask, genuinely, why, having a relatively vast choice among the suppliers of similar production, our clients and partners have chosen our Company and ТМ QUARCO?

    First of all, this is because the family of pharmaceutical equipment under QUARCO PHARM & MEDICAL EQUIPMENT trademark is rather broad and enables to meet the demands of enterprisers from different business segments: thus, QUARCO coaters can be used both in pharmaceutical and food industries, with a possibility to coat tablets, as well as dragee and chewing gums. The sphere of application of QUARCO packaging equipment (blister packaging, “SACHET” type bag and DoyPack type bag packaging, cardboard machines) is also extremely extensive and embraces pharmaceutics, food industry and cosmetology.  TM QUARCO accessory equipment (calibrators, lifting columns and “drum tumblers”) is popular with manufacturers of medicinal products, feed compounds, with enterprises from chemical, agrochemical and food industries.

    In other words, it is fair to say that pharmaceutical equipment under QUARCO PHARM & MEDICAL EQUIPMENT trademark is fairly universal and meets not only the demands of manufactures of solid and liquid therapeutic forms but also the demands of enterprises from other branches.

    Moreover, the production range of our Company includes such technologically complicated pharmaceutical equipment as lyophilic dryers, dryers with fluidized bed, and automatic lines of filling, sterilizing and sealing vials. Adequate supply of high-quality pharmaceutical equipment is unreachable without a careful and serious approach to the production issue, manufacture of customer-friendly equipment control systems, full preparation of relevant documents, and performing of start-up works after installation. Q-TECHNOLOGIES GROUP GMBH Company executes the whole range of the above-mentioned works and activities, so providing timely and robust supply of equipment needed by customers, which namely attracts our clients and partners and guides them to make   their final choice in favor of ТМ QUARCO equipment
    In fact, it is fair to say that the clients and partners acquire not only high-quality pharmaceutical equipment under ТМ QUARCO but also a full package of services regarding supply and start-up works, including supply of necessary spare parts and components and a 24-month warranty period.

    Finally, the production under QUARCO PHARM & MEDICAL EQUIPMENT trademark is not limited to the equipment introduced at the official website and in catalogues. Our clients refer to us with non-standard requests for: container equipment with particular characteristics and specific features, filling machines for both hard and soft gelatin capsules, lab lyophilic dryers, lab coaters, lab dryers with fluidized bed, etc. Nevertheless, a request being specific or non-standard by no means influences the speed of forwarding a business proposal to the Customer, nor does this delay delivery, nor does this lower quality of the supplied equipment, nor does this affect the whole package of services supplied by our Company. For us, the primary purpose is the maximum satisfaction of demands of our Client, and namely for this reason our customers have become loyal clients and partners of Q-TECHNOLOGIES GROUP GMBH Company, with many of whom we have built not only business but also long-term, genuinely friendly and partnership relationships.

    Thus, the answer to the question of the reasons for choosing pharmaceutical equipment under ТМ QUARCO by our partners is clear and is contained in the abbreviation of our trademark: QUA means QUAlity, R means Reliability, CO means Customer Oriented.

    To convenience our clients, Q-TECHNOLOGIES GROUP GMBH Company has representative offices in Russia, China and Ukraine.

    We are confident that the number of our customers will continuously grow, which means that the number of our partners and friends will grow correspondingly!

    We look forward to all new partners!

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